Michael Teitell

Michael Teitell, MD, PhD

Principal Investigator

Teitell Lab on Twitter
Phone (310) 206-6754

About

A Short Biography

Dr. Michael A. Teitell is the Director of the UCLA Jonsson Comprehensive Cancer Center, and President of the Jonsson Cancer Center Foundation. Dr. Teitell holds the Latta Endowed Chair in Pathology and is a full professor in the Departments of Pathology and Laboratory Medicine, with joint appointments in the Departments of Pediatrics and Bioengineering. He serves as Physician and Chief of the Division of Pediatric and Neonatal Pathology and he has been a member of the UCLA-JCCC since 1999. Dr. Teitell is also a member of the Molecular Biology Institute, the Broad Center of Regenerative Medicine and Stem Cell Research, AIDS Research Institute, and the California NanoSystems Institute at UCLA.

Dr. Teitell received concurrent B.S. and M.S. degrees from the UCLA College Honors Program as a Departmental Scholar in Chemistry and Biochemistry in 1985. He earned combined M.D. and Ph.D. degrees in the UCLA Medical Scientist Training Program in 1993 under the mentorship of Dr. Mitchell Kronenberg, current President and Chief Scientific Officer of the La Jolla Institute for Allergy and Immunology.  Dr. Teitell was a resident and clinical instructor in anatomic pathology at Brigham and Women’s Hospital and Harvard Medical School (1993–1995), and during this time he was also a research associate with Dr. Richard Blumberg. He was a resident in clinical pathology at UCSF and a post-doctoral researcher with Dr. Joe Gray (1995–1997). Dr. Teitell held a joint appointment at Children’s Hospital of Los Angeles as a pediatric pathology fellow and at UCLA as a clinical instructor in pathology (1997–1999).

Board certified in anatomic, clinical and pediatric pathology, Dr. Teitell joined the UCLA faculty as an assistant professor in 1999, and rose to the rank of full professor by 2008. He is director of the David Geffen School of Medicine Cancer Research Theme, co-director of the UCLA Tumor Immunology Training Program, co-director of the Broad Stem Cell Research Center Bioengineering Core, and an associate director of the UCLA-Caltech Medical Scientist Training Program (M.D., Ph.D. program). For UCLA, he serves as the NCAA Faculty Athletics Representative for Intercollegiate Athletics and holds posts on the Mountain Pacific Sports Federation (Chair, 2014–), Pac-12 Conference Diversity Leadership Committee (Chair, 2016–), and Pac-12 Conference Woman of the Year Nominating Committee (Chair, 2016–).   Dr. Teitell is also President of the UCLA Jonsson Cancer Center Foundation, which in the past five years has raised over $77 million.

Dr. Teitell’s previous professional and administrative experience includes appointments to the California Cancer Research Coordinating Committee (Chair, 2008), the UCLA Academic Senate Intercollegiate Athletics Committee (Chair, 2008–2014, ex officio 2014–), the NIH Cancer Center Site Visit Team and NIH Cancer Genetics Study Section (2004–2010) and the NIH Provocative Questions Review Panel (Chair, 2015).  Dr. Teitell has also organized national and international meetings, including the 2007 CNSI/CNBI Joint Meeting on NanoBiology, the 2007 ISCBM Conference on Development and Stem Cells, and the 2014 Cell Press Symposium on Stem Cell Energy Metabolism. He is a member of the American Association of Immunologists, the American Association for Cancer Research, the Biophysical Society, and the American Society for Biochemistry and Molecular Biology.

A renowned molecular immunologist and biochemist, Dr. Teitell’s research on the fundamental mechanisms of cancer formation and progression, particularly for B lymphocyte malignancies, has attained international acclaim. This led to projects in stem and cancer cell metabolism and the collaborative development of new approaches in cell engineering and response detection. Dr. Teitell is the recipient of the Stohlman Memorial Scholar Award from the Leukemia and Lymphoma Society of America, the Margaret E. Early Medical Research Trust Award, the FOCIS/Millenium Pharmaceuticals Award for Genomics Research, and he was elected to the American Society of Clinical Investigators (ASCI) in 2004 and to the Association of American Physicians (AAP) in 2017. 

Work Titles

  • Director, UCLA Health Jonsson Comprehensive Cancer Center
  • President, Jonsson Cancer Center Foundation
  • Associate Dean, David Geffen School of Medicine, Cancer Research and Care
  • Director, David Geffen School of Medicine Cancer Research Theme
  • Harrison and Lya Latta Endowed Chair in Pathology and Laboratory Medicine
  • Professor, Departments of Pathology, Pediatrics and Bioengineering
  • Director, T32 UCLA Tumor Immunology Training Program
  • NCAA Faculty Athletics Representative, UCLA Intercollegiate Athletics
  • Member, Broad Center of Regenerative Medicine & Stem Cell Research
  • Member, Molecular Biology Institute
  • Member, David Geffen School of
  • Medicine I3T Research Theme
  • Member, Cell & Developmental
  • Biology GPB Home Area
  • Member, Immunity, Microbes &
  • Molecular Pathogenesis GPB Home Area
  • Member, Molecular Pharmacology GPB Home Area

Contact Information

  • Work Email Address: mteitell@mednet.ucla.edu

  • Work Email Address: mteitell@ucla.edu

  • Fax Number: (310) 206-0657

  • Lab Number: (310) 206-6821

  • Office Phone Number: (310) 206-6754

  • Laboratory Address

    • 4-567 MRL
    • 675 Charles E. Young Drive South
    • Mailcode: 173216
    • Los Angeles, CA 90095

  • Office Address

    • 4-762 MRL
    • 675 Charles E. Young Drive South
    • Mail Code: 173216
    • Los Angeles, CA 90095

Education and Degree(s)

Degrees

  • M.D., UCLA School of Medicine, 1993
  • Ph.D., UCLA, 1991
  • M.S., UCLA, 1985
  • B.S., UCLA, 1985

Fellowship

  • 2000 David Paul Kane Scholar, Jonsson Cancer Center Foundation
  • 1999 Lymphoma Research Foundation of America Fellow
  • 1997 - 1999 Pediatric Pathology, Children's Hospital, Los Angeles (T. Triche)

Fellowship

  • 1995 - 1997 Clinical Pathology, UCSF (D. Stites and J. Gray)
  • 1991 - 1993 Department of Microbiology and Immunology, UCLA (M. Kronenberg)

Academic Experience

  • 2008 - Departments of Pathology and Laboratory Medicine, Pediatrics, and Bioengineering

Certifications

  • 2001 American Board of Pathology
  • 1997 American Board of Pathology

Publications

A selected list of publications:

  1. Teitell, M., Mescher, M.F., Olson, C.A., Littman, D.R. and Kronenberg, M. The Thymus Leukemia Antigen Binds Human and Mouse CD8. Journal of Experimental Medicine 174(5): 1131-1138, 1991 [PMCID: PMC2119000]
  2. Teitell, M., Damore, M.A., Sulur, G.G., Turner, D.E., Stern, M.-H., Said, J.W., Denny, C.T. and Wall, R. TCL1 Oncogene Expression in AIDS-Related Lymphomas and Lymphoid Tissues. Proceedings of the National Academy of Science, USA 96(17): 9809-9814, 1999 [PMCID: PMC22292] (contributing author)
  3. Hoyer, K.K., French, S.W., Turner, D.E., Nguyen, M.T.N., Renard, M., Malone, C.S., Knoetig, S., Qi, C.-F., Su, T.T., Cheroutre, H., Wall, R., Rawlings, D.J., Morse III, H.C. and Teitell, M. A. Dysregulated TCL1 Promotes Multiple Classes of Mature B-Cell Lymphoma. Proceedings of the National Academy of Sciences, USA, 99:14392-14397, 2002 [PMCID: PMC137894] (contributing author)
  4. Hoyer, K.K., Pang, M., Gui, D., Shintaku, I.P., Kuwabara, I., Liu, F.-T., Said, J.W., Baum, L.G. and Teitell, M.A. An Anti-Apoptotic Role for Galectin-3 in Diffuse Large B Cell Lymphomas. American Journal of Pathology, 164:893-902, 2004 [PMCID: PMC1614710] (contributing author)
  5. Teitell, M.A. and Pandolfi, P.P. Lymphoid Malignancies. In Holland, E.: Mouse Models of Cancer, 1st Ed., New York, J. Wiley & Sons, pp. 237-259, 2004 (contributing author)
  6. Teitell, M.A. TCL1 Family Oncoproteins: Co-activators of Transformation. Nature Reviews Cancer, 5:640-648, 2005 [PMID: 16056259; PMCID – In Process] (contributing author)
  7. Shen, R.R., Ferguson, D.O., Renard, M., Hoyer, K.K., Kim, U., Hao, X., Alt, F.W., Roeder, R.G., Morse III, H.C. and Teitell, M.A. Dysregulated TCL1 Requires the Germinal Center and Genome Instability for Mature B Cell Transformation. Blood 108:1991-1998, 2006 [PMCID: PMC1895536] (contributing author) Note: See Inside Blood: Janz, S. TCL1-induced germinal center B lymphomas in mice. Blood 108: 1791-1792, 2006
  8. Chen, H.-W., Rainey, R.N., Balatoni, C.E., Dawson, D.W., Troke, J.J., Wasiak, S., Hong, J., McBride, H., Koehler, C.M., Teitell, M.A., and French, S.W. Mammalian PNPase is an Intermembrane Space Ribonuclease that Maintains Mitochondrial Homeostasis. Molecular and Cellular Biology, 26:8475-8487, 2006 [PMCID: PMC1636764] (contributing author)
  9. Weihs, D., Mason, T.G. and Teitell, M.A. Bio-Microrheology: A Frontier in Microrheology. Biophysical Journal, 91:4296-4305, 2006 [PMCID: PMC1635658] (contributing author)
  10. Chen, H.-W., Koehler, C.M., and Teitell, M.A. Human Polynucleotide Phosphorylase: Location Matters. Invited, Trends in Cell Biology, 17:600-608, 2007 [PMID: 17983748; PMCID – In Process] (contributing author)
  11. Kuraishy, A.I., French, S.W., Sherman, M., Herling, M., Jones, D., Wall, R., and Teitell, M.A. TORC2 Regulates Germinal Center Repression of the TCL1 Oncoprotein to Promote B Cell Development and Inhibit Transformation. Proceedings of the National Academy of Sciences, USA, 104:10175-10180, 2007 [PMCID: PMC1891214] (contributing author)
  12. Dawson, D.W., Hong, J.S., Shen, R., French, S.W., Troke, J.T., Wu, Y.-Z., Chen, S.-S., Gui, D., Regelson, M., Marahrens, Y., Morse III, H.C., Said, J.W., Plass, C., and Teitell, M.A. Global Assessment of DNA Methylation in a Mouse Model of B Cell Lymphoma Identifies Epigenetic Silencing of a Variant Transcript of EphA7 in Lymphocytes. Oncogene, 26:4243-4252, 2007 [PMCID: PMC2756834] (contributing author)
  13. Memarzadeh, S., Xin, L., Mulholland, D.J., Mansukhani, A., Wu, H., Teitell, M.A., and Witte, O.N. Enhanced Paracrine FGF10 Expression Promotes Formation of Multifocal Prostate Adenocarcinoma and an Increase in Epithelial Androgen Receptor. Cancer Cell, 12:572-585, 2007 [PMCID: PMC2931420]
  14. Janz, S., Morse III, H.C., and Teitell, M.A. Mouse Models of Human Mature B- Cell and Plasma Cell Neoplasms. In Li, S: Mouse Models of Human Blood Cancers, The Jackson Laboratories, Springer Press, 179-225, 2008.
  15. Reed, J., Troke, J.J., Schmit, J., Han, S., Teitell, M.A.*, and Gimzewski, J.K.* Live Cell Interferometry Reveals Cellular Dynamism During Force Propagation. ACS Nano, 2:841-846, 2008 [PMCID: PMC2733939] (*co-contributing author)
  16. Wu, H., Kim, K.J., Mehta, K., Paxia, S., Sundstrom, A., Anantharaman, T., Kuraishy, A.I., Doan, T., Ghosh, J., Pyle, A., Clark, A., Lowry, W., Fan, G., Baxter, T., Mishra, B., Sun, Y., and Teitell, M.A. Copy Number Variant Analysis of Human Embryonic Stem Cells. Stem Cells, 26:1484-1489, 2008 [PMCID: PMC3901366] (contributing author)
  17. Teitell, M.A. and Pandolfi, P.P. Molecular Genetics of Acute Lymphoblastic Leukemia. Annual Reviews of Pathology 4:175-198, 2009 [PMID: 18783329] (contributing author)
  18. Frank, M.J., Dawson, D.W., Bensinger, S.J., Hong, J.S., Knosp, W.M., Xu, L., Balatoni, C.E., Allen, E.L., Shen, R.R., Bar-Sagi, D., Martin, G.R., and Teitell, M.A. Expression of sprouty2 Inhibits B-Cell Proliferation and is Epigenetically Silenced in Mouse and Human B-Cell Lymphomas. Blood, 113:2478-2487, 2009 [PMCID: PMC2656273] (contributing author)
  19. Chin, M., Mason, M., Xie, W., Volinia, S., Singer, M., Peterson, C., Ambartsumyan, G., Aimiuwu, O., Richter, L., Zhang, J., Khvorostov, I., Ott, V., Grunstein, M., Benvenisty, N., Croce, C.M., Clark, A., Baxter, T., Pyle, A., Teitell, M.A., Pellegrini, M., Plath, K., and Lowry, W. Induced Pluripotent Stem Cells and Embryonic Stem Cells are Distinguished by Gene Expression Signatures. Cell Stem Cell, 5:111-123, 2009 [PMCID: PMC3448781]
  20. Wang, G., Chen, H.-C., Oktay, Y., Zhang, J., Allen, E.L., Smith, G.M., Fan, K.C., Hong, J.S., French, S.W., McCaffery, J.M., Lightowlers, R.N., Morse III, H.C., Koehler, C.M., and Teitell, M.A. PNPASE Regulates RNA Import into Mitochondria. Cell, 142:456-467, 2010 [PMCID: PMC2921675] (contributing author) Note: See Cell Preview by Endo, T., Yamano, K., and Yoshihisa, T. Mitochondrial Matrix Reloaded with RNA. Cell, 2010 Aug 6; 142(3): 362-363. Note: See Cell Leading Edge, Cell 2010 Aug 6 issue
  21. Sherman, M.H., Kuraishy, A.I., Desphpande, C., Hong, J.S., Cacalano, N.A., Gatti, R.A., Manis, J.P., Damore, M.A., Pellegrini, M., and Teitell, M.A. AID-Induced Genotoxic Stress Promotes B Cell Differentiation in the Germinal Center via ATM and LKB1 Signaling. Molecular Cell, 39: 873-885, 2010 [PMCID: PMC2945612] (contributing author)
  22. Morse III, H.C., Ward, J.M. and Teitell, M.A. Animal Models of Human B Lymphoid Neoplasms. In Magrath, I: The Lymphoid Neoplasms, 3rd Ed., London, Arnold, pp. 281-292, 2010
  23. Wu, T.-H., TeSlaa, T., Kalim, S., French, C.T., Maghadam, S., Wall, R., Miller, J.F., Witte, O.N., Teitell, M.A.*, and Chiou, P.-Y.* Photothermal Nanoblade for Large Cargo Delivery into Mammalian Cells. Analytical Chemistry, 83:1321-1327, 2011 [PMCID: PMC3166650] (*co-contributing author) Note: News Highlight in Chemical & Engineering News
  24. Sherman, M.H., Bassing, C.H., and Teitell, M.A. DNA Damage Response Regulates Cell Differentiation. Trends in Cell Biology, 21: 312-319, 2011 [PMCID: PMC3089693] (contributing author)
  25. French, C.T., Toesca, I.J., Wu, T.-H., Teslaa, T., Beaty, S.M., Wong, W., Liu, M.H., Schroeder, I.S., Chiou, P.-Y., Teitell, M.A., and Miller, J.F. Dissection of the Burkholderia Intracellular Lifecycle Using a Photothermal Nanoblade. Proceedings of the National Academy of Sciences, USA, 108: 12095-12100, 2011 [PMCID: PMC3141958]
  26. Huang, Y., Park, Y., Wang-Zhu, Y., Larange, A., Arens, R., Bernardo, I., Olivares-Villagomez, D., Mendez-Fernandez, Y.V., Herndler-Brandstetter, D., Abraham, N., Grubeck-Loebenstein, B., Schoenberger, S.P., Van Kaer, L., Kronenberg, M., Teitell, M. A., and Cheroutre, H. Affinity-Based Selection of Mucosal CD8 Memory T Cells by an MHC Class I Molecule. Nature Immunology, 12:1086-1095, 2011 [PMCID: PMC3197978]
  27. Reed, J., Chun, J., Zangle, T.A., Kalim, S., Hong, J.S., Pefley, S.E., Zheng, X., Gimzewski, J.K., and Teitell, M.A. Rapid, Massively Parallel Single-Cell Drug Response Measurements Via Live Cell Interferometry. Biophysical Journal, 101:1025-1031, 2011 [PMCID: PMC3164181] (contributing author)
  28. Zhang, J., Khvorostov, I., Hong, J.S., Oktay, Y., Vergnes, L., Nuebel, E., Wahjudi, P.N., Setoguchi, K., Wang, G., Do, A., Jung, H.-J., McCaffery, J.M., Kurland, I.J., Reue, K., Lee, W.N.P., Koehler, C.M., and Teitell, M.A. UCP2 Regulates Energy Metabolism and Differentiation Potential of Human Pluripotent Stem Cells. EMBO Journal, 30:4860-4873, 2011 [PMCID: PMC4972131] (contributing author). Note: See Have You Seen? by Shyh-Chang, N., Zheng, Y., Locasale, J.W., and Cantley, L.C. Human Pluripotent Stem Cells Decouple Respiration from Energy Production. EMBO Journal, 30: 4851-4852, 2011 [PMCID: PMC3242981]
  29. Zhang, J., Nuebel, E., Daley, G.Q., Koehler, C.M., and Teitell, M.A. Metabolic Regulation in Pluripotent Stem Cells During Reprogramming and Self-Renewal. Cell Stem Cell, 11:589-595, 2012 [PMCID: PMC3492890] (contributing author)
  30. Zhang, J., Nuebel, E., Wisidagama, D.R.R., Setoguchi, K., Hong, J.S., Van Horn, C. M., Imam, S.S., Vergnes, L., Malone, C.S., Koehler, C.M., and Teitell, M.A. Measuring Energy Metabolism in Cultured Cells, Including Human Pluripotent Stem Cells and Differentiated Cells. Nature Protocols, 7:1068-1085, 2012 [PMCID: PMC3819135] (contributing author)
  31. Dabir, D., Hasson, S.A., Setoguchi, K., Johnson, M.E., Wongkongkathep, P., Douglas, C.J., Zimmerman, J., Damoiseaux, R., Teitell, M.A., and Koehler, C.M. MitoBloCK-6: A Small Molecule Inhibitor of Redox-Regulated Protein Translocation in Mitochondria.  Developmental Cell, 25:81-92, 2013 [PMCID: PMC3726224]
  32. Zangle, T.A., Chun, J., Zhang, J., Reed, J., and Teitell, M.A. Quantification of Biomass and Cell Motion in Human Pluripotent Stem Cell Colonies. Biophysical Journal, 105:593-601, 2013 [PMCID: PMC3736662] (contributing author) Note: See New and Notable by Kusuma, S. and Gerecht, S.  Fast and Furious: The Mass and Motion of Stem Cells. Biophysical Journal, 105:837-838, 2013 [PMCID: PMC3752099]
  33. Xie, Y., Zhang, J., Lin, Y., Meng, X., Wisidagama, D.R.R., Cinkornpumin, Koehler, C.M., Malone, C.S., Teitell, M.A.*, and Lowry, W.E.* Defining Role of Oxygen Tension in Human Neural Cell Fate. Stem Cell Reports, 3(5): 743-757, 2014 [PMCID: PMC4235163] (*co-contributing author)
  34. Teslaa, T. and Teitell, M.A.  Techniques to Monitor Glycolysis. In Galluzzi, L. and Kroemer, G., eds.Elsevier, Inc.: Oncometabolism, Methods In Enzymology, 542: 91-114, 2014 (contributing author)
  35. Zangle, T.A. and Teitell, M.A. Live Cell Mass Profiling: An Emerging Approach in Quantitative Biophysics. Nature Methods, 11(12): 1221-1228, 2014 [PMCID: PMC4319180] (contributing author)
  36. Teitell, M.A. Adult Stemlike Cells Exclude ‘Older’ Mitochondria. Cell Metabolism, 21:658-659, 2015 [PMCID: PMC4428616] (contributing author)
  37. Teslaa, T and Teitell, M.A. Pluripotent Stem Cell Energy Metabolism: An Update. EMBO Journal, 34(2): 138-153, 2015 [PMCID: PMC4337063] (contributing author)
  38. Wu, Y.-C., Wu, T.-H., Clemens, D.L., Lee, B.-Y., Wen, X., Horwitz, M.A., Teitell, M.A.*, and Chiou, P.-Y.* Massively Parallel Delivery of Large-Sized Cargo into Mammalian Cells with Light Pulses. Nature Methods, 12(5): 439-444, 2015 [PMCID: PMC5082232] (*co-contributing author)
  39. Wu, T.-H., Sagullo, E., Case, D., Zheng, X., Li, Y., Hong, J.S., TeSlaa, T., Patananan, A.N., McCaffery, J.M., Niazi, K., Braas, D., Koehler, C.M., Graeber, T.G., Chiou, P.-Y., and Teitell, M.A. Mitochondrial Transfer by Photothermal Nanoblade Restores Metabolite Profile in Mammalian Cells. Cell Metabolism, 23(5):921-929, 2016 [PMCID: PMC5062745] (contributing author). Note: See Research Highlights: ‘Nanoblade’ Slips Organelle into Cells’, Nature, 533: 295, May 19, 2016. Note: See News in Brief: ‘Mitochondrial Transfer’, Nature Medicine, 22: 575, June, 2016. Note: See Inner Workings: “Light-Controlled Cellular Surgery” Proceedings of the National Academy of Sciences, USA, 113: 9663-9664, 2016. Note: See Commentary: ‘Cellular Star Trek: A Laser-Based Shuttle Transfers Mitochondria into Cells’, Molecular Metabolism, 5(10): 805-806, 2016 [PMCID: PMC5034483]
  40. Patananan, A.N., Wu, T.-H., Chiou, P.-Y., and Teitell, M.A. Modifying the Mitochondrial Genome. Invited, Cell Metabolism, 23(5): 785-796, 2016 [PMCID: PMC4864607] (contributing author)
  41. TeSlaa, T, Chaikovsky, A.C., Lipchina, I., Escobar, S.L., Hochedlinger, K., Huang, J., Graeber, T.G., Braas, D., and Teitell, M.A. -Ketoglutarate Accelerates the Initial Differentiation of Primed Human Pluripotent Stem Cells. Cell Metabolism, 24(3): 485-493, 2016 [PMCID: PMC5023506] (contributing author)
  42. Waters, L.R., Ahsan, F.M., Wolf, D.M., Shirihai, O., and Teitell, M.A. Initial B Cell Activation Induces Metabolic Reprogramming and Mitochondrial Remodeling. iScience, 5: 99-109, 2018 [PMCID: PMC6123864] (contributing author)
  43. Zhang, J., Zhao, J., Dahan, P., Lu, V., Zhang, C., Li, H., and Teitell, M.A. Metabolism in Pluripotent Stem Cells and Early Mammalian Development. Cell Metabolism, 27(2): 332-338, 2018 [PMID: 29114683; PMCID – In Process] (contributing author)
  44. Dhir, A., Dhir, S., Lukasz, B.S., Jimenez, L., Teitell, M., Rötig, A., Crow, Y.J., Rice, G.I., Duffy, D., Tamby, C., Nojima, T., Munnich, A., Schiff, M., de Almeida, C.R., Rehwinkel, J., Dziembowski, A., Szczesny, R.J., and Proudfoot, N.J. Mitochondrial Double Stranded RNA Triggers Antiviral Signalling in Humans. Nature, 560(7717), 238-242, 2018 [PMCID: PMC6570621]
  45. Lu, V. and Teitell, M.A. aKG: A ‘magic’ metabolite in early germ cell development. Invited, EMBO Journal, 38(1). pii: e100615. doi: 10.15252/embj.2018100615, 2018 [PMCID: PMC6315287] (contributing author)
  46. Lu, V., Dahan, P., Ahsan, F.M., Patananan, A.N., Roy, I.J., Torres Jr., A., Nguyen, R.M.T., Huang, D., Braas, D., and Teitell, M.A. Mitochondrial Metabolism and Glutamine are Essential for Mesoderm Differentiation of Human Pluripotent Stem Cells. Cell Research, 29(7):596-598, 2019 [PMCID: PMC6796950] (contributing author)
  47. Patananan, A.N., Sercel, A.J., Wu, T.-H., Ahsan, F.M., Torres Jr., A., Kennedy, S.A.L., Vandiver, A., Collier, A.J., Mehrabi, A., Van Lew, J., Zakin, L., Rodriguez, N., Sixto, M., Tadros, W., Lazar, A., Sieling, P.A., Nguyen, T.L., Dawson, E.R., Braas, D., Golovato, J., Cisneros, L., Vaske, C., Plath, K., Rabizadeh, S., Niazi, K., Chiou, P.-Y., and Teitell, M.A. Pressure-Driven Mitochondrial Transfer Pipeline Generates Mammalian Cells of Desired Genetic Combinations and Fates. Cell Reports, Dec 29;33(13):108562. 2020 [PMCID: PMC7927156] (contributing author)
  48. Nguyen, T.L., Polanco, E.R., Patananan, A.N., Zangle, T.A., and Teitell, M.A. Cell Viscoelasticity is Linked to Fluctuations in Cell Biomass Distributions. Scientific Reports, May 4; 10(1):7403, 2020 [PMCID: PMC7198624] (contributing author)
  49. Sercel, A.J., Patananan, A.N., Man, T., Wu, T.-H., Yu, A.K., Guyot, G.W., Rabizadeh, S., Niazi, K.R., Chiou, P.-Y., and Teitell, M.A. Stable Transplantation of Human Mitochondrial DNA by High-Throughput, Pressurized Mitochondrial Delivery. eLife, Jan 13;10: e63102. doi: 10.7554/eLife.63102. 2021 [PMCID: PMC7864630] (contributing author)
  50. Sercel, A.J., Carlson, N.M., Patananan, A.N., and Teitell, M.A. mtDNA Dynamics in Reprogramming to Pluripotency. Trends in Cell Biology, Apr;31(4):311-323. doi: 10.1016/j.tcb.2020.12.009, 2021 [PMCID:  PMC7954944] (contributing author)
  51. Lu, V., Roy, I.J., and Teitell, M.A. Nutrients in the Fate of Pluripotent Stem Cells. Cell Metabolism, 2021 Nov 2;33(11):2108-2121. doi: 10.1016/j.cmet.2021.09.013. Epub 2021 Oct 12. [PMCID: PMC8568661] (contributing author)
  52. Nguyen, T.L., Pradeep, S., Judson-Torres, R.L., Reed, J., Teitell, M.A.*, and Zangle, T.A.* Quantitative Phase Imaging: Recent Advances and Expanding Potential in Biomedicine. Invited, ACS Nano, Aug 23;16(8):11516-11544. doi: 10.1021/acsnano.1c11507, 2022 [PMID: 35916417; PMCID – In Process] (co-contributing author)
  53. Lu, V., Roy, I.J., Torres Jr., A., Joly, J.H., Ahsan, F.M., Graham, N.A., and Teitell, M.A. Glutamine-Dependent Signaling Controls Pluripotent Stem Cell Fate. Developmental Cell, 57(5):610-623.e8. 2022 [PMCID: PMC8930616] (contributing author)
  54. Tebon, P.J., Wang, B., Markowitz, A.L., Davarifar, A., Tsai, B.L., Krawczuk, P., Gonzalez, A.E., Sartini, S., Murray, G., Nguyen, H.T.L., Tavanaie, N., Nguyen, T.L., Boutros, P.C., Teitell, M.A.*, and Soragni, A.* Drug Screening at Single-Organoid Resolution via Bioprinting and Interferometry. Nature Communications, 2023 Jun 6;14(1):3168. doi: 10.1038/s41467-023-38832-8. [PMCID: PMC10244450]. (*co-contributing author)
  55. Velez MA, Glenn BA, Garcia-Jimenez M, Cummings AL, Lisberg A, Nañez A, Radwan Y, Lind-Lebuffe JP, Brodrick PM, Li DY, Fernandez-Turizo MJ, Gower A, Lindenbaum M, Hegde M, Brook J, Grogan T, Elashoff D, Teitell MA, Garon EB. Consent document translation expense hinders inclusive clinical trial enrolment. Nature. 2023 Aug;620(7975):855-862. doi: 10.1038/s41586-023-06382-0. Epub 2023 Aug 2. [PMCID: in process]

A selected list of patents:

  1. Optical Cytometry, US Patent No. 8,599,383, 12/3/2013, James K. Gimzewski, Jason C. Reed, and Michael A. Teitell
  2. High-Speed On Demand Droplet Generation and Single Cell Encapsulation Driven by Induced Cavitation, US Patent No. 9,176,504, 11/3/2015, Pei-Yu E. Chiou, Ting-Hsiang S. Wu, Sung-Yong Park, and Michael A. Teitell
  3. Methods and Compositions for Regulating RNA Import into Mitochondria, US Patent No. 9,238,041, 1/19/2016, Geng Wang, Carla M. Koehler, and Michael A. Teitell
  4. Pulsed Laser Triggered High-Speed Microfluidic Switch and Applications in Fluorescent Activated Cell Sorting, US Patent No. 9,364,831, 6/14/2016, Pei-Yu E. Chiou, Ting-Hsiang Wu, and Michael A. Teitell
  5. Use of Live Cell Interferometry with Reflective Floor Observation Chamber to Determine Changes in Mass of Mammalian Cells, US Patent No. 9,810,683, 11/7/2017, James K. Gimzewski, Jason C. Reed and Michael A. Teitell
  6. High-Speed On Demand Microfluidic Droplet Generation and Manipulation, US Patent No. 10,071,359, 9/11/2018, Yu-Chun Kung, Pei-Yu E. Chiou, Ting-Hsiang S. Wu, Yue Chen, and Michael A. Teitell
  7. Single Cell Drug Response Measurements via Live Cell Interferometry, US Patent No. 10,203,331, 2/12/2019, Jason C. Reed and Michael A. Teitell
  8. Pulsed Laser Triggered High Speed Microfluidic Switch and Applications in Fluorescent Activated Cell Sorting, US Patent No. 10,226,768, 3/12/2019, Pei-Yu E. Chiou, Ting-Hsiang S. Wu, and Michael A. Teitell
  9. High-Speed On Demand Droplet Generation and Single Cell Encapsulation Driven by Induced Cavitation, US Patent No. 10,232,368, 3/19/2019 Pei-Yu E. Chiou, Ting-Hsiang S. Wu, Sung-Yong Park, and Michael A. Teitell
  10. Photothermal Substrates for Selective Transfection of Cells, US Patent No. 10,435,661, 10/8/2019, Pei-Yu E. Chiou, Ting-Hsiang S. Wu, Sheraz Butt Kalim, and Michael A. Teitell
  11. Efficient Delivery of Large Cargos into Cells on a Porous Substrate, US Patent No. 10,472,651, 11/12/2019, Pei-Yu E. Chiou, Ting-Hsiang S. Wu, and Michael A. Teitell
  12. Modulators of mitochondrial protein import, US Patent No. 10,758,513, 9/1/2020, Carla M. Koehler, Samuel A. Hasson, Kiyoko Miyata, Michael A. Teitell, Deepa Dabir
  13. Methods for Efficient Intracellular Delivery using Anisotropic Magnetic Particles, US Patent No. 10,787,657, 9/29/2020, Pei-Yu E. Chiou, Ming-Yu Lin, Yi-Chien Wu, Jessica Zhou, and Michael A. Teitell
  14. High-Speed on Demand Microfluidic Droplet Generation and Manipulation, US Patent No. 10,780,413, 9/22/2020, Yu-Chun Kung, Pei-Yu E. Chiou, Ting-Hsiang S. Wu, Yue Chen, and Michael A. Teitell
  15. Optical Cytometry to Determine Cell Mass Changes in Response to a Biologically Active Agent, US Patent No. 10,802,012, 10/13/2020, James K. Gimzewski, Jason C. Reed, and Michael A. Teitell
  16. Selecting and Isolating Desirable T Lymphocytes by Change in Mass Responses, US Patent No. 10,900,956, 1/26/2021, Michael A. Teitell, Thomas A. Zangle, Owen N. Witte, and Daina Burnes Linton
  17. High-Throughput Cargo Delivery into Live Cells using Photothermal Platforms, US Patent No. 10,982,217, 4/20/2021, Yi-Chien Wu, Ting-Hsiang S. Wu, Pei-Yu E. Chiou, and Michael A. Teitell
     

Honors and Awards

  • 2001 FOCIS/Millenium Pharmaceuticals Award for Genomics Research
  • 2001 Lymphoma Research Foundation Junior Faculty Award
  • 2003-2008 Scholar Award, Leukemia and Lymphoma Society
  • 2004 Elected to American Society of Clinical Investigators (ASCI)
  • 2005 Margaret Early Medical Research Trust Award
  • 2008 Stohlman Scholar, Leukemia and Lymphoma Society
  • 2012-present Lya and Harrison Latta Endowed Chair in Pathology, UCLA
  • 2013 Dr. Pinar Ozand Memorial Lecture, 12th Annual AOCCN Meeting, Riyadh, Saudi Arabia
  • 2014 Co-organizer, Cell Press (CM/CSC) meeting on Stem Cell Metabolism
  • 2015 Visiting Professor, CHLA Department of Pathology and Laboratory Medicine
  • 2016 National Football Foundation Faculty Athletics Representative Award
  • 2017 Harrison and Lya Cordova Latta Lecture, UCLA
  • 2017 Elected to Association of American Physicians (AAP)
  • 2018 Jerome B. Block Memorial Lecture on Oncology, LA BioMed, Torrance, CA
  • 2019 Harry J. Sacks Endowed Lectureship Cedars-Sinai Medical Center, Beverly Hills, CA

Membership and Service

  • Molecular Biology Institute
  • Broad Stem Cell Research Center (BSCRC)
  • American Society for Biochemistry and Molecular Biology (ASBMB)
  • California NanoSystems Institute (CNSI)
  • American Association for Cancer Research (AACR)
  • American Association of Immunologists (AAI)
  • Institute for Cell Mimetic Space Exploration (CMISE)
  • American Society of Clinical Investigators
  • UCLA Association of Chemists and Biochemists
  • UCLA AIDS Research Institute
  • Jonsson Comprehensive Cancer Center
  • Institute for Stem Cell Biology and Medicine (ISCBM)
  • Sigma Xi Scientific Society
  • 2015 Visiting Professor, Children's Hospital Los Angeles, Department of Pathology and Laboratory Medicine
  • 2013 Scientific Advisory Board, Department of NanoMedicine, Methodist Research Institute, Houston, TX